The Optalert BlinQTM system uses blepharometry (the study of eyelid movements) and patented algorithms to accurately quantify drowsiness or wakefulness, against the validated Johns Drowsiness Scale (JDS). This future-proofed approach to clinical development can advance clinical drug trial timelines and deliver new therapies to market faster. The data can also be expanded further to allow in depth analysis for other biomarkers to be identified.
Using infrared (IR) reflectance, infrared light, which is invisible to the user, illuminates the upper eyelid. A sensor detects the reflection of IR light from the eyelids and an on-board processor digitises the reflections at 500 times per second. The sensor technology is mounted inside glasses frames where sunglasses or prescription lenses can be fitted. Glasses frames were chosen to house the sensors to make them as unobtrusive as possible and to ensure the patient is not restricted in their movements.
Each pair of glasses goes through a onetime fitment process, to ensure the device is precisely fitted to the patient. The fitment process takes approximately 5-10 minutes for trained technicians to perform. The glasses are simple to use and available in wired or wireless format, depending on the application used.